Capsule Ferrous Sulfate/Folic Acid/Zinc Sulfate 47/0.5/22.5 mg

Pharmacological class

Nutritional Supplement (mineral)



Iron deficiency anemia (prophylaxis and treatment).

Iron requirements maybe increased and/ or supplementation may be necessary in the following persons or conditions (based on documented iron deficiency): Pregnancy ,Breastfeeding,   Achlorhydria , Blood loss (excessive), Burns, Gastrectomy, Hemodialysis, Hemorrhage, Infants (as liquid oral dosage form) , Intestinal diseases,  individuals with conditions that cause chronic blood loss (e.g. peptic ulcer , hemorrhoids , hookworms).

Burns, Gastrectomy,  Hemodialysis, Hemorrhage, Infants, Intestinal, individuals with conditions that cause chronic blood (e.g. peptic ulcer , hemorrhoids , hookworms).

Folic acid deficiency (prophylaxis and treatment).

Supplementation may be necessary in the following persons or conditions Alcoholism, Anemia hemolytic, Fever (chronic), Gastrectomy,  Hemodialysis (chronic), Infants (as liquid oral dosage form), Intestinal diseases (celiac disease, tropical spur, persistent diarrhea), Malabsorption syndromes associated with hepatic-biliary disease, hepatic function impairment stress prolonged, some unusual diets , pregnancy, breast feeding , before  conceptation, alcoholism with cirrhosis.

Zinc deficiency (prophylaxis and treatment) Deficiency of zinc may lead to growth retardation, hypogonadism in males, anorexia (possibly due to changes in taste and smell),depressed mental function, dermatitis, impaired wound-healing, suppressed immune function, diarrhea, and abnormal vitamin A metabolism with impaired night vision.

Recommended intakes may be increased and/or supplementation may be necessary in the following conditions (based on documented zinc deficiency): Alcoholism, Burns, Cirrhosis of the liver, Diabetes mellitus, Eating disorders (anorexia nervosa, bulimia), Gastrectomy,

Genetic disorders (acrodermatitis enteropathica, Down's syndrome, sickle cell anemia, thalassemia), Hemodialysis, Infants-premature, Infections (chronic), due to decreased immune responses, Intestinal diseases (celiac, Crohn's, diarrhea, spur, ulcerative colitis), Intestinal parasitism, Malabsorption syndromes associated with pancreatic insufficiency (pancreatic disease, cystic fibrosis), Renal diseases (nephrotic syndrome, renal failure, uremia) , Short bowel syndrome, Skin disorders (exfoliative dermatoses, psoriasis), Stress prolonged, Trauma prolonged, Some unusual diets, pregnancy, breast feeding.

Pregnancy Category

Pregnancy Category: C [1st trimester]


Only use in the second and third trimesters.

Breast-feeding: Excreted in breast milk.

Pediatrics, Geriatrics. 

Instruct patient to take FERFOZIMAN  1 hour before or 2 hours after eating dairy products, Eggs, Coffee, Tea containing tannic acid, whole-grain breads and cereals, antacids, calcium supplements, or poultry , fiber, phosphorus, or Phytates. Milk or milk product, alcohol.

Contraindication & Drug interaction

Sensitivity to Ferrous sulfate, Folic Acid, Zinc Sulfate or other medications. Pernicious anemia, Copper deficiency.                                                                                                                         

Except under special circumstances, this medication should not be used when the following medical problems exist:

Hemochromatosis, Hemosiderosis, Other anemic conditions, Porphyria cutanea tarda.

Risk-benefit should be considered when the following medical problems exist:

Alcoholism , active or in remission, Allergies, Asthma, Cardiovascular disease, Hepatitis or hepatic function impairment, Kidney disease acute, infectious, Intestinal tract inflammatory conditions, such as enteritis, colitis, diverticulitis, and ulcerative colitis or Peptic ulcer, Rheumatoid arthritis, sensitivity to iron.

Pernicious anemia, Sensitivity to folic acid.

Copper deficiency (zinc supplementation may induce copper deficiency or further decrease serum copper concentrations).


Drug Interactions

Acetohydroxamic , Penicillamine, and possibly other heavy metal chelators, Cimetidine, Deferoxamine, Dimercaprol, Etidronate, Fluoroquinolones, Pancreatin, Pancrelipase, Tetracyclines(supplements should be given 2 hours after the administration of tetracycline). Calcium supplements

Analgesics (long-term use), Anticonvulsants, Carbamazepine, Estrogens, Oral contraceptives, Phenobarbital, Primidone, Hydantoin (an increase in hydantoin dosage may be necessary for patients who receive folic acid supplementation), Aluminum- or magnesium-containing Antacids.

(Patients should be advised to take antacids at least 2 hours after supplement), Antibiotics, Cholestyramine ,Methotrexate, Pyrimethamine, Triamterene , Trimethoprim, Sulfonamides, including sulfasalazine, Copper supplements (large doses of zinc may inhibit copper absorption in the intestine; zinc supplements should be taken at least 2 hours after the administration of copper supplements). Thiazide diuretics (thiazide diuretics have been found to increase urinary zinc excretion).

Foods: Alcohol, Tea, Coffee, Eggs, Foods or medications containing bicarbonates, carbonates, oxalates or phosphates. Phosphorus containing foods, such as milk and milk product or poultry, Phytates (found in bran and whole-grain breads and cereals).

Usual Adult Dose

Oral; 1 capsule daily.

 Deficiency (prophylaxis)-oral:


 Fe ++mg

Folic acid mcg

Zn++ mg

Adolescent& adult males




Adolescent & adult females




Pregnant Women


400 to 800


Breast-feeding Mothers




Deficiency (treatment)-Treatment dose is individualized by prescriber based on severity of deficiency.


Side Effects

Those indicating need for medical attention:

allergic reaction, bronchospasm, eryhema, fever, and general malaise, skin rash or itching, leukopenia; neutropenia; sideroblastlc anemia, secondary to zinc-induced copper deficiency, Abdominal or stomach pain, cramping, or soreness, dyspepsia; epigastric pain; hematologic abnormalities.

Those indicating need for medical attention only if they continue or are bothersome:

Incidence more frequent: constipation; diarrhea; nausea; vomiting,  

Incidence less frequent or rare: Irritation, darkened urine, heart burn.

Note: stools commonly become dark green or black. This is caused by the presence of unabsorbed iron and is harmless.


Store below 30°C (86 °F), Protect from light. Keep the medicine in the box.


24 capsules in one box.

Each capsule contains:

Red pellets: iron (as ferrous sulfate) 47mg

Yellow pellets: Folic Acid 500mcg, zinc (as Zinc Sulfate) 22.5mg

White pellets: Sugar





Address: 10th Km Karaj Road (Jadeh makhsoos),Tehran,Iran
Tel: (+98 ) 21 44504121-3
Email: info@loghman-med.com
© 2014 LOGHMAN Pharmaceutical & Hygienic Co.